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Clinical Research

@ClinicalResearch

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44trials
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Health Story

Published clinical studies and research from PubMed and peer-reviewed journals.

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Arthritis
Published Research
Feb 5, 2026

SAM-e (S-Adenosylmethionine) for Hip and Knee Osteoarthritis

Joint pain, stiffness, and reduced mobility in the hip and/or knee due to osteoarthritis, affecting walking and daily ac...

Intervention: S-Adenosylmethionine (SAM-e)
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ADHD
Published Research
Feb 5, 2026

Omega-3 Fatty Acids for ADHD Symptoms in Children (Meta-Analysis)

Attention difficulties, hyperactivity, impulsivity, and difficulty focusing on tasks in children with ADHD symptoms.

Intervention: Omega-3 Fatty Acids (EPA/DHA)
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High Blood Pressure
Published Research
Feb 5, 2026

Garlic Supplements for High Blood Pressure (Meta-Analysis)

Elevated blood pressure readings, particularly systolic blood pressure above normal range, increasing cardiovascular ris...

Intervention: Garlic Extract
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Insomnia
Published Research
Feb 5, 2026

Chamomile Extract for Sleep Quality in Elderly

Poor sleep quality in older adults, including difficulty falling asleep, frequent waking, and feeling unrested in the mo...

Intervention: Chamomile (Matricaria chamomilla) Extract
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Allergies
Published Research
Feb 5, 2026

Quercetin for Seasonal Allergic Rhinitis (Hay Fever)

Seasonal allergy symptoms including sneezing, runny nose, nasal congestion, itchy eyes, and sleep disturbance during pol...

Intervention: Quercetin Phytosome
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Joint Pain
Published Research
Feb 5, 2026

Stinging Nettle for Base-of-Thumb Osteoarthritis Pain

Pain at the base of the thumb or index finger from osteoarthritis, making gripping and pinching movements painful and di...

Intervention: Stinging Nettle Leaf (Urtica dioica)
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Sinus Issues
Published Research
Feb 5, 2026

Bromelain for Chronic Rhinosinusitis Symptoms

Chronic sinus congestion, facial pressure, difficulty breathing through nose, post-nasal drip, and reduced sense of smel...

Intervention: Bromelain (Pineapple Enzyme)
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Dry Skin
Published Research
Feb 5, 2026

Collagen Peptides for Skin Elasticity and Hydration

Loss of skin elasticity, dryness, fine lines, and visible signs of skin aging. Skin that feels less firm and supple than...

Intervention: Collagen Hydrolysate (Peptides)
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Blood Sugar Issues
Published Research
Feb 5, 2026

Apple Cider Vinegar for Blood Sugar Control in Type 2 Diabetes

Elevated blood sugar levels in type 2 diabetes, including high fasting glucose, elevated HbA1c, and blood sugar spikes a...

Intervention: Apple Cider Vinegar
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Fatigue
Published Research
Feb 5, 2026

Iron Supplementation for Unexplained Fatigue in Non-Anemic Women

Persistent tiredness and low energy in women without anemia, often with low iron stores (ferritin). Fatigue affecting wo...

Intervention: Ferrous Sulfate (Iron)
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Anxiety
Published Research
Feb 5, 2026

Lavender Oil (Silexan) for Generalized Anxiety Disorder

Persistent worry, restlessness, difficulty relaxing, muscle tension, sleep problems, and physical symptoms of anxiety af...

Intervention: Silexan (Lavender Oil Preparation)
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Acne
Published Research
Feb 5, 2026

Tea Tree Oil Gel for Mild to Moderate Acne

Facial acne with pimples, blackheads, whiteheads, and occasional inflamed lesions. Mild to moderate severity affecting a...

Intervention: Tea Tree Oil (Melaleuca alternifolia) 5% Gel
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Brain Fog
Published Research
Feb 5, 2026

Lion's Mane Mushroom for Mild Cognitive Impairment

Mental cloudiness, difficulty concentrating, forgetfulness, slower thinking, and trouble finding words. Mild cognitive d...

Intervention: Hericium erinaceus (Lion's Mane) Extract
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Burnout
Published Research
Feb 5, 2026

Rhodiola Rosea Extract for Stress-Related Fatigue and Burnout

Mental and physical exhaustion from prolonged stress, difficulty concentrating, reduced motivation, feeling overwhelmed ...

Intervention: Rhodiola Rosea Extract (SHR-5)
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Fatigue
Published Research
Feb 5, 2026

Vitamin D3 for Self-Perceived Fatigue in Deficient Adults

Persistent tiredness, low energy, feeling drained despite adequate sleep. Fatigue that interferes with daily activities ...

Intervention: Vitamin D3 (Cholecalciferol)
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Insomnia
Published Research
Feb 2, 2026

Magnesium Bisglycinate for Sleep Quality in Adults

Difficulty falling asleep, poor sleep quality, non-restorative sleep, and daytime fatigue. Insomnia symptoms without und...

Intervention: Magnesium Bisglycinate (Glycinate)
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Prostate
Published Research
Feb 2, 2026

Saw Palmetto for Benign Prostatic Hyperplasia (BPH) - Negative Result

Lower urinary tract symptoms from enlarged prostate including frequent urination, urgency, weak stream, incomplete bladd...

Intervention: Saw Palmetto (Serenoa repens) Extract
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Menopause Symptoms
Published Research
Feb 2, 2026

Black Cohosh for Menopausal Hot Flashes

Vasomotor symptoms of menopause including hot flashes, night sweats, flushing, and associated sleep disturbance. Can sig...

Intervention: Black Cohosh (Cimicifuga racemosa) Extract
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Migraines
Published Research
Feb 2, 2026

Feverfew CO2 Extract (MIG-99) for Migraine Prevention

Recurrent migraine attacks with or without aura, occurring multiple times per month. Throbbing headache, often unilatera...

Intervention: Feverfew (Tanacetum parthenium) Extract
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Arthritis
Published Research
Feb 2, 2026

Boswellia Serrata Extract for Knee Osteoarthritis

Knee pain, stiffness, and reduced mobility due to osteoarthritis. Pain worsens with activity and may limit daily activit...

Intervention: Boswellia Serrata Extract
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Muscle Cramps
Published Research
Feb 2, 2026

Tart Cherry Juice for Exercise-Induced Muscle Soreness

Delayed onset muscle soreness (DOMS) after strenuous exercise, characterized by muscle tenderness, stiffness, reduced ra...

Intervention: Tart Cherry Juice (Montmorency)
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Constipation
Published Research
Feb 2, 2026

Psyllium Fiber for Chronic Constipation

Infrequent bowel movements (less than 3 per week), hard stools, straining, incomplete evacuation, and abdominal discomfo...

Intervention: Psyllium Husk (Ispaghula)
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Migraines
Published Research
Feb 2, 2026

Butterbur (Petasites) Extract for Migraine Prevention

Episodic migraines occurring 2-6 times per month, with pulsating headache, nausea, photophobia and/or phonophobia. Attac...

Intervention: Butterbur Root Extract (Petadolex)
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Nausea & Vomiting
Published Research
Feb 2, 2026

Ginger for Pregnancy-Related Nausea and Vomiting

Nausea and vomiting during pregnancy (morning sickness), typically occurring in first trimester. May be persistent throu...

Intervention: Ginger Root Extract
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Eczema
Published Research
Feb 2, 2026

Vitamin D Supplementation for Severe Atopic Dermatitis

Chronic inflammatory skin condition with intense itching, dry scaly patches, redness, and skin barrier dysfunction. Symp...

Intervention: Vitamin D3 (Cholecalciferol)
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High Cholesterol
Published Research
Feb 2, 2026

Red Yeast Rice for Lowering LDL Cholesterol

Elevated LDL cholesterol levels (>130 mg/dL), often asymptomatic but associated with increased cardiovascular disease ri...

Intervention: Red Yeast Rice Extract
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High Blood Pressure
Published Research
Feb 2, 2026

Beetroot Juice for Lowering Blood Pressure in Hypertension

Elevated blood pressure (systolic >140 mmHg and/or diastolic >90 mmHg), often asymptomatic but increasing cardiovascular...

Intervention: Beetroot Juice (Dietary Nitrate)
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Depression
Published Research
Feb 2, 2026

Saffron Extract for Mild to Moderate Depression

Persistent low mood, loss of interest in activities, fatigue, difficulty concentrating, changes in sleep and appetite. M...

Intervention: Saffron (Crocus sativus) Extract
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Migraines
Published Research
Feb 2, 2026

High-Dose Riboflavin (Vitamin B2) for Migraine Prevention

Recurring migraine headaches with throbbing pain, often one-sided, accompanied by nausea, photophobia, and phonophobia. ...

Intervention: Riboflavin (Vitamin B2)
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Bloating
Published Research
Feb 1, 2026

Probiotics for Abdominal Bloating in IBS

Belly bloating, uncomfortable fullness, and gas. Digestive discomfort related to IBS.

Intervention: Multi-strain Probiotics (L. acidophilus, B. lactis)
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Insomnia
Published Research
Feb 1, 2026

Valerian Root Extract for Sleep Quality

Trouble falling asleep and not feeling rested. Mild sleep problems without a medical cause.

Intervention: Valerian Root (Valeriana officinalis)
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Common Cold
Published Research
Feb 1, 2026

Elderberry Extract for Cold and Flu Symptoms

Cold and flu symptoms - stuffy nose, sore throat, cough, fever, body aches.

Intervention: Elderberry (Sambucus nigra) Extract
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Joint Pain
Published Research
Feb 1, 2026

Glucosamine Sulfate for Knee Osteoarthritis Progression

Knee pain and stiffness from arthritis. Hard to walk, climb stairs, or stay active.

Intervention: Glucosamine Sulfate
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Anxiety
Published Research
Feb 1, 2026

Omega-3 Fish Oil for Anxiety and Inflammation

Feeling anxious, worried, or on edge. Tension and nervousness affecting daily life.

Intervention: Omega-3 Fatty Acids (EPA/DHA)
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Urinary Tract Infections
Published Research
Feb 1, 2026

Cranberry Products for Urinary Tract Infection Prevention

Getting bladder infections over and over. Painful urination, urgency, and discomfort.

Intervention: Cranberry Extract
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Heart Palpitations
Published Research
Feb 1, 2026

Coenzyme Q10 for Chronic Heart Failure (Q-SYMBIO Trial)

Shortness of breath, feeling tired all the time, weak, trouble with everyday activities due to heart failure.

Intervention: Coenzyme Q10 (Ubiquinone)
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Common Cold
Published Research
Feb 1, 2026

Zinc Acetate Lozenges for Common Cold Duration

Sore throat, stuffy nose, sneezing, coughing, and feeling run down. The typical cold.

Intervention: Zinc Acetate Lozenges
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Blood Sugar Issues
Published Research
Feb 1, 2026

Berberine for Type 2 Diabetes Blood Sugar Control

High blood sugar, feeling tired after meals, increased thirst, trouble managing diabetes with diet alone.

Intervention: Berberine HCL
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47%
Joint Pain
Published Research
Feb 1, 2026

Curcumin Extract for Knee Osteoarthritis Pain

Knee pain when walking or climbing stairs, morning stiffness, trouble with everyday activities.

Intervention: Curcumin (Curcugen extract)
47% improvement (1 reported)
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59%
IBS
Published Research
Feb 1, 2026

Enteric-Coated Peppermint Oil for IBS Symptoms

Belly pain, bloating, gas, and irregular bathroom habits. Symptoms get worse after eating.

Intervention: Peppermint Oil (enteric-coated)
59% improvement (1 reported)
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Stress
Published Research
Feb 1, 2026

L-Theanine for Stress-Related Symptoms in Healthy Adults

Everyday stress causing mild anxiety, tension, and trouble sleeping. Not a diagnosed anxiety disorder.

Intervention: L-Theanine
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Stress
Published Research
Feb 1, 2026

Ashwagandha Root Extract for Reducing Stress and Anxiety

Feeling stressed out all the time, trouble concentrating, tired but wired, hard to relax.

Intervention: Ashwagandha (KSM-66 extract)
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Insomnia
Published Research
Feb 1, 2026

Melatonin for Primary Sleep Disorders (Meta-Analysis)

Hard time falling asleep, not sleeping long enough, and feeling tired during the day.

Intervention: Melatonin
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Insomnia
Published Research
Feb 1, 2026

Magnesium Supplementation for Primary Insomnia in Elderly

Trouble falling asleep, waking up too early, and not feeling rested. Common in older adults.

Intervention: Magnesium (elemental)