ShareMyTrial
Sign In
Constipation
Published Research

Psyllium Fiber for Chronic Constipation

473 participants

Symptoms Studied

Infrequent bowel movements (less than 3 per week), hard stools, straining, incomplete evacuation, and abdominal discomfort. Chronic symptoms affecting quality of life.

Research Hypothesis

Psyllium is a soluble fiber with high water-holding capacity that forms a gel, increasing stool bulk and moisture while normalizing transit time.

Intervention Tested

Psyllium Husk (Ispaghula)

5g psyllium husk twice daily (10g total), mixed with water or other liquid, taken with meals

Duration: 4-8 weeks

Study Results

Before Treatment

Adults meeting Rome III/IV criteria for chronic constipation with reduced stool frequency and hard stools.

After Treatment

66% of patients responded to psyllium treatment vs 41% to placebo. Stool frequency increased by 3 bowel movements per week. Psyllium as effective or better than osmotic laxatives.

Timeline to Improvement

Improvements in stool frequency within 1-2 weeks; optimal effects after 4+ weeks

Side Effects

Mild bloating and gas initially (usually resolves). Must take with adequate water to prevent choking/obstruction.

Source

Conclusion

Psyllium is an effective, well-tolerated first-line treatment for chronic constipation, increasing stool frequency and improving stool consistency.

Comments (0)

Did this work for you?

Share your experience

Sign in to vote

Try It Yourself

Create your own trial based on this study and share your results.

Replicate This Trial

Similar Trials

More trials for Constipation coming soon.

Browse all Constipation trials