Coenzyme Q10 for Chronic Heart Failure (Q-SYMBIO Trial)

420 participants

Shortness of breath, feeling tired all the time, weak, trouble with everyday activities due to heart failure.

CoQ10 helps heart cells make energy. People with heart failure often have low CoQ10 levels.

100mg CoQ10 (ubiquinone) three times daily (300mg total), taken with meals containing fat

Duration: 2 years

Before Treatment

Moderate to severe heart failure limiting daily life. On standard heart medications.

After Treatment

Cut risk of dying from heart problems in half. Fewer hospital visits. Better energy and quality of life.

Improvements in symptoms by 16 weeks, with survival benefits emerging over 2 years

Very well tolerated. No significant side effects compared to placebo.

Coenzyme Q10 for Chronic Heart Failure (Q-SYMBIO Trial)
Mortensen SA, et al. JACC Heart Fail. 2014;2(6):641-649

CoQ10 reduced deaths and hospitalizations by half in people with heart failure. A breakthrough finding.

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